Lapho ukhetha ibhentshi-indawo yokomisa iqhwa ephezulu noma okomisa okokuqandisa kwemboni kanye ne-lyophilizer yezimboni, abasebenzisi badinga ukugxila kumapharamitha angukhiye abalulekile ukuze baqinisekise ukuthi umshini wokumisa iqhwa ungahlangabezana nezidingo ezijwayelekile zokumisa iqhwa{1}}zokomisa kanye ne-lyophilization processing.
Ipharamitha ewumgogodla wokuqala ukunemba kokulawula izinga lokushisa. Isisetshenziswa esihle kakhulu se-vacuum freeze dryer sidinga ukuqonda ukulungiswa kwezinga lokushisa okunembile ebangeni elibanzi lokushisa eliphansi-. Ukunemba kokulawula izinga lokushisa kwebhentshi laselabhorethri-i-lyophilizer ephezulu kufanele ifinyelele ku-±0.1℃, futhi isomisi esiqandisayo sezimboni kufanele siqinisekise ukulawulwa okuzinzile kwezinga lokushisa ngaphakathi kwamadigri angu-±0.5 ukuze kugwenywe umehluko wesampula kanye nekhwalithi yomkhiqizo.
Ipharamitha eyinhloko yesibili ukuzinza kwe-vacuum degree. I-Lyophilization kanye neqhwa-ukoma kuncike endaweni ehlanzekile ephansi{2}}yokucindezela. Isomisi sokuqandisa esifanelekayo singagcina inani levacuum elizinzile isikhathi eside ngaphandle kokuguquguquka okusobala, okuyisihluthulelo sokuqinisekisa ukufakwa kwe-sublimation okufanayo nokomiswa kwezinto.
Ipharamitha yesithathu amandla efriji e-condenser. I-condenser iyingxenye eyinhloko yomshini wokumisa iqhwa ukuze ubambe umhwamuko wamanzi. Umthamo wesiqandisi oqinile ungaminyanisa ngokushesha umhwamuko wamanzi, uthuthukise ukuqhwa-ukusebenza kahle kokoma, futhi uvimbele umhwamuko wamanzi ukuthi ungaphindi{3}}ungene endaweni yokomisa ukuze uthinte ikhwalithi ye-lyophilization.
Ipharamitha yesine iwukumisa ukufana. Ikhwalithi ephezulu-yekhwalithi ephezulu ye-lyophilizer yezimboni kanye nebhentshi{2}}isomisi esiqandisa phezulu singaqinisekisa umphumela wokoma ongaguquguquki wazo zonke izinto ezisegumbini, akukho ndawo ngaphansi-kokoma noma ngaphezulu{4}}kokoma{4}}okuqaphela ikhwalithi ehlanganisiwe ye-lyophilization yeqoqo ngalinye lamasampula nemikhiqizo.
Ngaphezu kwalokho, ukuzinza kokusebenza kwemishini kanye nokulandelelwa kwedatha nakho kuyizinkomba ezibalulekile zokuhlola. Imishini yokomisa iqhwa echwepheshe enezimiso ezinhle kakhulu inganciphisa ngempumelelo amaphutha okukhiqiza kanye nokuhlola, futhi ithuthukise izinga lokufaneleka lokuqandisa{1}}imikhiqizo eqediwe yokumisa kanye ne-lyophilization.
