I-vacuum freeze dryer iyisisetshenziswa sokumisa esisebenza kahle kakhulu esisusa umswakama ezintweni ezibonakalayo{0}}ngokwehlisa izinga lokushisa eliphansi. Asetshenziswa kakhulu ezimbonini zokudla, ezemithi, zebhayoloji, nezimboni zamakhemikhali. Isimiso sabo esiyinhloko ukwehlisa izinga lokushisa elingaphansi kwendawo yokuqandisa endaweni ye-vacuum, okubangela umswakama ukuba ufinyelele ngokuqondile endaweni eqinile ukuya esimweni esinegesi, ngaleyo ndlela ugweme ukulimala kwezithako ezisebenzayo zezinto ezibangelwa ukushisa okuphezulu. Okulandelayo imininingwane yendlela yokusetshenziswa kusukela ezicini ezintathu:{4}}ngaphambi kokulungiswa komsebenzi, izinqubo zokusebenza, nezinyathelo zokuphepha.
Ukulungiselela{0}}kwangaphambilini
Ukuhlolwa Kwezisetshenziswa: Qinisekisa ukuthi isicupho esibandayo, iphampu yevacuum, isistimu yokushisisa, kanye nesistimu yokulawula kuhlelo lokusebenza olujwayelekile. Hlola ukuthi izinga lokushisa elibandayo le-cold trap lifinyelele inani elimisiwe yini (ngokuvamile elidinga -ukupholisa kuqala libe ngaphansi -40℃), uma izinga likawoyela wephampu yevacuum lingaphakathi kwebanga elijwayelekile, nokuthi amaringi okuvala aqinile yini.
Ukwelashwa Ngaphambi Kwezinto Ezibalulekile: Yenza ukwelashwa-kwangaphambi kokuba kube yiqhwa ngokuya nezici ezibonakalayo. Isibonelo, izinto zokudla zidinga ukumiswa eqhweni -ku-30 degree kuya -40℃amahora angu-12-24 ukuze kuqinisekiswe ukubanda okuphelele; izinto zemithi zidinga amazinga okuqandisa alawulwayo ukuze kugwenywe ukulimala kwekristalu. Ukungaqandisi okunganele kungaholela ekuweni ngesikhathi se-sublimation, kuthinte ikhwalithi yomkhiqizo oqediwe.
Ukulayishwa kanye Nesakhiwo: Sakaza okokusebenza ngokulinganayo kumathileyi wezinto ezibonakalayo, ngogqinsi olunconywayo luka-5-10mm. Amathreyi ezinto eziningi kufanele agcine isikhala (isb, 38mm) ukugwema ukuvimbela ukusakazeka komhwamuko. Ngezinto zokwakha ezinezakhi eziguquguqukayo, sebenzisa izinto zokupakisha ezinokungena komoya okuhle.
Izinqubo Zokusebenza
Ngaphambi-Isigaba Sokuqandisa: Setha izinga lokushisa langaphambili-eliqandisiwe (-40℃to -50℃) kanye nesikhathi (lungisa kuye ngenani lezinto ezibonakalayo, ngokuvamile amahora angu-2-4) usebenzisa iphaneli yokulawula ehlakaniphile. Phakathi nalesi sigaba, qinisekisa ukuthi izinga lokushisa elibandayo lizinzile ukuze ugweme ukwakheka ngokweqile kwekristalu yeqhwa ngenxa yokushintshashintsha kwezinga lokushisa.
I-Vacuum and Sublimation Drying: Ngemva{0}}okuqhwanda ngaphambili, qala iphampu yevacuum ukuze unciphise ingcindezi yesistimu ibe ngaphansi kuka-10Pa (ukuthola i-vacuum evamile engu-5Pa ngaphansi{3}}kokulayishwa). Kuleli qophelo, iqhwa entweni liqala ukuncibilika, lidinga amandla avela kusistimu yokushisa eqhubayo (isb., ukushisa kweshalofu). Izinga lokushisa lokushisa kufanele lenyuswe kancane kancane (kunconywa ukuthi liqale ukusuka ku--20℃, likhuphuke ngo-5-10℃isigaba ngasinye) ukuze kugwenywe ukushisa kwendawo.
I-Desorption Drying Stage: Lapho izinga lokushisa lempahla lisondela kuzinga lokushisa le-ambient, isigaba sokumisa se-desorption siyaqala. Kuleli qophelo, izinga le-vacuum lidinga ukuncishiswa ngokuqhubekayo (libe ngaphansi kwe-2 Pa), futhi izinga lokushisa leshalofu lenyuke laya ku-30-50℃ukuze kukhishwe amanzi aboshwe asele. Phakathi nalesi sigaba, isibonisi sesampula sezinga lokushisa sidinga ukugadwa okuqhubekayo ukuze kuvinjelwe izinga lokushisa elidlulele ekubangeleni ukushintshashintsha kwezinto.
Vala shaqa kanye Nesampula: Ngemva kokoma, qala ngokuvala isistimu yokushisisa, bese ucisha iphampu yevacuum ngemva kokuba izinga lokushisa lempahla lehlile lafinyelela kuzinga lokushisa legumbi. Okokugcina, faka i-nitrogen yokomisa ukuze uphule i-vacuum futhi ususe impahla. Ngezinto -zenani eliphezulu, kunconyiwe ukusebenzisa-inkinobho eyodwa yokusebenza kwe-defrost kagesi ukuze ubuyisele isisetshenziswa esimweni saso esijwayelekile.
